Allostatic Load Biomarkers of Chronic Stress and Impact on Health and Cognition, Neuroscience and Biobehavioral Reviews (2009)

Scientific Paper

The allostatic load model expands the stress-disease literature by proposing a temporal cascade of multisystemic physiological dysregulations that contribute to disease trajectories. By incorporating an
allostatic load index representing neuroendocrine, immune, metabolic, and cardiovascular system functioning, numerous studies have demonstrated greater prediction of morbidity and mortality over
and beyond traditional detection methods employed in biomedical practice. This article reviews theoretical and empirical work using the allostatic load model vis-a` -vis the effects of chronic stress on physical and mental health. Specific risk and protective factors associated with increased allostatic load are elucidated and policies for promoting successful aging are proposed.

This resource is related to Course V: Balance – Anabolism and Catabolism. If you are interested in purchasing this course from our on-demand library of courses click here.

[Homeostasis. Allostatic Load. Chronic Stress. Cognition.]