COURSE IX: Methylation Cycle

This lesson focuses on the critical and often underappreciated biochemical cycle of methylation. We learn of its importance in a vast array of essential biological processes, from the sculpting of the body within the mother’s womb, to detoxification and cell membrane health. We then look at the related interlocking cycles that affect production of neurotransmitters and the powerful antioxidant, glutathione. Focus is turned to the detail of these enzymatic pathways, and to factors that can clog and slow down these cycles including genetic SNPs, nutrient depletion, stress and toxicity. We are then better able to appreciate the individuals who are vulnerable to problems in these pathways and laboratory measures that may be of help confirm methylation issues. Two key vitamins – B12 and folate are of particular importance and are explored, as well as the means to remedy imbalances and keep the methyl groups flowing.