COURSE III: Burning Sugar – Glucose Metabolism and its Role in Insulin Dysregulation

This lesson covers in great depth the downstream consequences of raised blood glucose and insulin. Starting by reviewing the metabolic pathways of energy generation and storage, the hormonal balance of ‘anabolism’ and ‘catabolism’ is considered. The physiology of digestion and processing dietary carbohydrates is then explored, giving an appreciation of ‘hyperinsulinaemia’ as an often unrecognised but important state of imbalance. Clinical manifestations and contributory drivers for a raised insulin are looked at in depth. We then bring Type 1 and type 2 Diabetes into focus, clarifying their distinct aetiologies. Finally, a historical perspective on the treatment of Diabetes offers insights into helping to address and indeed reverse this common dis-ease.